Preliminary Phytochemical Screening, Free radical Scavenging and Antimicrobial activities of Justicia tranquebariensis Linn. Balamurugan G.1, Arunkumar M. P.1, Muthusamy P.2,*, Anbazhagan S.1 1Department of Pharmaceutical Biotechnology, C. L. Baid Metha College of Pharmacy Old Mahabalipuram Road (Rajiv Gandhi Salai), Jyothi Nagar, Thoraipakkam, Chennai 600 097. Tamil Nadu 2Department of Pharmacognosy, Madras Medical College, Chennai-600 003. Tamil Nadu *Corresponding Author E-mail: muthu_p99@yahoo.com
Abstract The aerial portions of the plant Justica tranquebariensis Linn were successively extracted with chloroform and ethanol by soxhlet extraction. The extracts were vaccum dried and subjected to antibacterial (Staphylococcus aureus, Bacillus subtillis, Escherichia coli and Klebsiella pneumoniae) and antifungal (Aspergillus niger and Candida albicans) screening by agar disc diffusion method. Minimum Inhibitory Concentration required for cessation of microbial growth was evaluated by Agar streak dilution method. Preliminary phytochemical screening was performed and different Phytoconstituents present in the extracts were identified. The ethanolic extract of the aerial portions of Justicia tranquebariensis was tested for free radical scavenging activity using 1, 1 Diphenyl Picryl Hydrazyl radicals. Top Keywords Justicia tranquebariensis, Antibacterial, Antifungal, Free radical scavenging Phytoconstituents, Minimum Inhibitory Concentration (MIC). Top |