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Research Journal of Pharmacy and Technology
Year : 2008, Volume : 1, Issue : 3
First page : ( 179) Last page : ( 181)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.

Preliminary Phytochemical screening and Anti oxidant activities of Ethanolic extract of Caesalpinia sappan Linn

Gunasekaran Balamurugan*, Muralidharan P., Pandiselvi A., Amutha P.

Department of Pharmacology and Toxicology, C. L. Baid Metha College of Pharmacy, Old Mahabalipuram Salai, Jyothi Nagar, Thoraipakkam, Chennai-600 097, Tamil Nadu, India

*Corresponding Author E-mail: balamurugangunasekaran@gmail.com

Abstract

The ethanolic extract of heart wood of the plant Caesalpinia sappan obtained was dried under vacuum and subjected to anti oxidant activity using in vitro models such as DPPH radical scavenging, nitric oxide scavenging, and hydroxyl radical scavenging. Preliminary phytochemical screening was carried out to find different phyto constituents present in the ethanol extract of C. sappan. The extract exhibited the presence of important compounds such as flavanoids, glycosides, protein. The extract exhibited significant antioxidant activity which was comparable with the standards employed.

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Keywords

Antioxidant, Caesalpinia sappan, DPPH, hydroxyl free radical, nitric oxide, phyto constituents.

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