Phytochemical screening and antioxidant activity of cananga odorata extract Jiea Chew Khe1, Fuloria Shivkanya1, Subrimanyan Vetriselvan2, Sekar Mahendran3, Sathasivam Kathiresan V.4, Kayarohanam Saminathan5, Wu Yuan Seng6, Velaga Venkata Sathya Saiappala Raju7, Janakiraman Ashok Kumar8, Maziz Mohammad Nazmul Hasan2, Fuloria Neeraj Kumar1,* 1Faculty of Pharmacy, AIMST University, Kedah08100, Malaysia 2Faculty of Medicine, Bioscience and Nursing, MAHSA University, Bandar Saujana Putra42610, Malaysia 3Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of MedicinePerak, Ipoh30450, Malaysia 4Faculty of Applied Science, AIMST University, Kedah08100, Malaysia 5Faculty of Bio-economy and Health Sciences, Geomatika University CollegeKuala Lumpur54200, Malaysia 6Centre for Virus and Vaccine Research & Department of Biological Sciences, School of Medical and Life Sciences, Sunway University, Subang Jaya, Selangor, Malaysia 7Faculty of Pharmacy, MAHSA University, Bandar Saujana Putra42610, Malaysia 8Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur56000, Malaysia *Corresponding Author E-mail: neerajkumar@aimst.edu.my
Online published on 14 June, 2022. Abstract Plants are the natural source for the antioxidants from plants source is boon for the investigators. Present study was aimed to study the antioxidant activity and phytochemical screening of Cananga odorata (Lam.) Hook. f. & Thomson extract. Study involved preparation hydroalcoholic extract of Cananga odorata leaves (HECOL) using maceration method, followed by its phytochemical screening and antioxidant activity. The HECOL was subjected to determination of total phenolic content (TPC) and total flavonoid content (TFC), and DPPH (1,1-Diphenyl-2-picryl hydrazyl) radical scavenging assay for determination of antioxidant activity. Maceration of C. odorata using hydroalcoholic solvent offered dark brown colored HECOL. Phytochemical screening of HECOL exhibited presence of carbohydrates, mucilage, fats and oils, volatile oils, anthraquinone glycosides, flavonoids, alkaloids, tannins and phenolic compounds. For TPC the gallic acid equivalent of HECOL was found to be 0.507 mg GAE/g. Whereas for TFC, the rutin equivalent of HECOL was found to be 0.2224mg RE/g. The antioxidant activity of HECOL was estimated to be 120.44µg/ml (IC50). Based on the experimental results, present study concludes that HECOL possess the significant antioxidant potential. This study also recommends that antioxidant activity potential of C. odorata leaves should be further explored using different solvent extracts. Top Keywords Canaga odorata, Total phenolic content, Gallic acid, Total flavonoid content, Antioxidant activity. Top |