Development and validation of HPLC method for quantification of favipiravir in tablet Kalshetti M. S.*, Adlinge Sagar G. Department of Pharmaceutical Quality Assurance, D. S. T. S. Mandal's College of Pharmacy, Solapur - 413004, Maharashtra, India *Corresponding Author E-mail: mskalshetti@gmail.com
Online published on 14 June, 2022. Abstract Hplc method has been developed and validated for the quantification of Favipiravir in tablet formulation The chromatographic separation was achieved by using Luna® Phenomenex Cs(150x4.6 mm,5µm) with the mobile phase comprising of water and methanol in the ratio of 95:5v/v. The flow rate was 1ml/min and the separated Favipiravir was detected at 229 nm. The retention time of Favipiravir was 4.3 minutes. The linearity data showed good linear relationship (r2= 0.9997) within the concentration range of 10–50 µg/ml. The method was successfully validated in accordance to the ICH guidelines and method was found to be sensitive, accurate, precise, and reproducible. Top Keywords Favipiravir, RP-HPLC, Validation, Method development, Method validation. Top |