Biological screening and structure activity relationship of benzothiazole Bhagdev Khyati1,*, Sarkar Sibaji2 1Dr. Subhash Technical Campus, Faculty of Pharmacy, Khamdhrol Road, Junagadh, Gujarat, India 2Nobel Pharmacy College, Bhesan Road, Junagadh, Gujarat, India *Corresponding Author E-mail: khyatiiibhupta@gmail.com
Online Published on 08 June, 2022. Abstract Benzothiazole is a heterocyclic compound having nitrogen and sulphur. It's a bicyclic compound with a thiazole with benzene ring fused together. As per a review of the literature, benzothiazole is a primary moiety for the development of anticancer, antidiabetic, antioxidant, analgesic, and anti-inflammatory, antibacterial, antifungal, antiviral, anticonvulsant, antidepressant, antioxidant, and hepatoprotective agents. As a result, a list of biologically active benzothiazole derivatives has indeed been compiled in this study. The structure-activity relationship is analyzed based on the biological activities of benzothiazole derivatives and their substitution pattern. We also examined the mechanism of action of various benzothiazole derivatives, which can benefit researchers in the creation of new benzothiazole derivatives. Top Keywords Anticancer, Antidiabetic, Antioxidant, Benzothiazole, Hepatoprotective, SAR. Top |