Preparation of Apamarg kshar tablet and assessment of In vitro potential against urolithiasis (Mutrakrichra) Baghel Dileep Singh1,***, Singh Saurabh1, Pandey Narendra Kumar1, Kumar Bimlesh1,**, Mittal Amit1,*, Chaudhary Anand Kumar2, Mittal Anu3, Singh Amrik4 1School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India 2Department of Rasa Shastra and Bhaishjya Kalpana (Ayurvedic Pharmaceutics), Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, India 3Department of Chemistry, Guru Nanak Dev University Collage, Patti, Tran Taran, Punjab, India 4School of Hotel Management and Tourism, Lovely Professional University, Punjab, India **Corresponding Author E-mail: bimlesh.12474@lpu.co.in
*amit.13145@lpu.co.in
***dileep.15210@lpu.co.in
Online published on 20 February, 2023. Abstract Background Urolithiasis (Mutrakricchra) is an age-old disorder which has multi-factorial etiological as well as associated with re-occurrence. It is standout among the most troubling disorders related to urinary tract. Acharya Sushruta, a pioneer in the art of surgery, described the root causes and management of urolithiasis (Mutrakricchra). In present day restorative practice, a lot of the management/treatment choices are available which begins from the utilization of uresis-elevating specialist to dietary or nourishing enhancement consumption. Amalgamating the Ayurvedic principle/concept with current medicinal practice is a promising methodology used for the management of urolithiasis (Mutrakricchra) now a days. Objective To prepare apamarg kshar and evaluate its potential against Urolithiasis (Mutrakrichra) by In-vitro technique. Materials and Methods Apamarg kshar were prepared as per the methodology mentioned in Rasatarangni and the prepared Kshar is compressed in tablet dosage form. Various parameters of apmarg kshar tablets were evaluated. Results Physicochemical and stability studies have not shown any remarkable variations with prepared tablet dosage form. In-vitro studies shows that 82 % of crystal inhibition at 550 μg/ml. Conclusion The prepared tablet dosage form of Apamarg Kshar does not have remarkable variation during physicochemical and stability studies. The developed dosage form produces promising result in vitro against Urolithiasis (Mutrakrichra). Top Keywords Mutrakrichra, Apamarg kshar, Tablet, Stability studies, Antiurolithic, Urolithiasis. Top |