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Research Journal of Pharmacy and Technology
Year : 2022, Volume : 15, Issue : 5
First page : ( 2093) Last page : ( 2096)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2022.00346

Status of zinc, iron and some biochemical parameters in patients with polycythemia

Wafaa Al-Zuhairi Sh.*, Hassan Ekhlas Abdallah**, Abdulmajeed Alzahraa Ibrahim***

Department of Chemistry, College of Science, University of Diyala, Baquba, Diyala, Iraq

*Corresponding Author E-mail: wafaa.chem@gmail.com

**ekhlasbiochemistry@gmail.com

***zahraa1987.zo@gmail.com

Online published on 20 February, 2023.

Abstract

The goal of this study is to determine the concentration of total zinc, iron, ESR, PCV, Hb, CBC in the serum of patients with polycythemia vera. These results are indicated that age of patient and control group Iraq males are to some extend similar. Whereas, average value of ESR ±SD for patient and control groups were (8.36± 4.41) and (15.40± 5.10), respectively. It was clearly indicated that ESR for patient higher than control group. The erythrocyte sedimentation rate (ESR) is decreased due to an increase in zeta potential. While, the average iron ±SD for patient and control group were (35.12 ± 8.21) and (23.48 ± 2.40) respectively. The level of zinc shows no significant difference between polycythemic and control gropes. Also show that there was a highly significance in packed cell volume between patient groups (51.49±4.62) when compared with control groups (36.30±3.22). The mean ±SD of Hb and WBC for patient and control group were (16.08 ± 1.14) (12.40 ± 0.68) and (12.04 ± 3.17) (8.21 ± 1.48) respectively. These results are showed that Hb, WBC of patient strongly higher compering to control group (p>0.05). the majority of patients were at the age between (41-50) years with percentage of (30.76%), (31-40) years with a percentage (25.64%) and (20-30) years with a percentage (23.07%). While age groups between (51-60) years were (12.82%) and age groups (>60) years were (7.7%). The result show that (2.5) percent of patients had PCV level less than normal, (38.5) percent of patients had normal level and (59) percent of patients showed concentration more than normal as shown in (Table 4). There are (5.1) percent of patients showed level less than normal, (53.8) percent of patients had normal level and (41) percent of patients showed concentration more than normal. The current study has been shown that the concentration of biochemical parameters is influenced by polycythemia.

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Keywords

Polycythemia, Zinc, Iron, Patients.

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