Comparative pharmacotherapeutic effectiveness of therapeutic ointments in infectious keratoconjunctivitis in cattle Boranbayeva K. E.1,*, Zamanbekov N. A.1, Sattarova R. S.2, Spiridonov G. N.3, Zhylgeldiyeva A. A.1, Turzhigitova Sh. B.1 1Kazakh National Agrarian Research University, 8 Abay Avenue, Almaty, 050010, Kazakhstan 2Kazakh Scientific Research Veterinary Institute LLP, 223 Raiymbek Avenue, Almaty, 050000, Kazakhstan 3Federal Center of Toxicological, Radiation and Biological Safety, Scientific Town - 2, Kazan, 420075, Russian FederationRussia *Corresponding Author E-mail: 17karla@mail.ru
Online Published on 10 October, 2023. Abstract The analysis of the presented data shows that keratoconjunctivitis is quite often registered in cattle. Therefore, new medicinal substances have been developed for its treatment, namely, a polycomponent ointment and a phyto-ointment from local plant raw materials. As a result of the conducted research, reliable data were obtained indicating the beneficial effect of the developed ointments on individual biochemical blood parameters in sick animals. Studies have established that the complex application of the developed ointments contributes to the bio-correction and bio-normalization of metabolic processes in the body of sick animals, which is expressed by a significant increase in the quantitative values of hematological parameters, total protein and its fractional composition, β-lysine, lysozyme, lactoferrin, and bactericidal activity of blood serum. In the course of treatment, the greatest therapeutic effectiveness was established in the 3rd experimental group of animals, which used a combined treatment regimen with the alternating use of multicomponent ointment the Kazakh Scientific Research Veterinary Institute LLP (KazSRVI) and phyto-ointment KerKon. After applying the combined scheme, 33.3% of animals recovered by the 10th day from the start of treatment, and the full recovery of the majority of sick animals occurred within 11-16 days (66.7%). The obtained results of the research and production experiment showed that the most acceptable method was the use of a combined treatment regimen for sick animals, where the absolute effectiveness was 100%, compared to 80% in the control group. Top Keywords Keratoconjunctivitis, Polycomponent ointment, Phyto-ointment, Medicinal plant, Effectiveness, Immune status. Top |