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Research Journal of Pharmacy and Technology
Year : 2023, Volume : 16, Issue : 11
First page : ( 5347) Last page : ( 5353)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2023.00866

Hippobroma longiflora (L.) G. Don: Comparative phytochemical screening and potential activities of flower and leaf by GC-MS

Dewi Nabilla Sinta, Susilo Susilo*

Department of Biology Education, Faculty of Teacher Training and Education, Universitas Muhammadiyah Prof. DR. HAMKA, East Jakarta, Indonesia, 13830

*Corresponding Author E-mail: susilo@uhamka.ac.id

Online Published on 5 February, 2024.

Abstract

Hippobroma longiflora (L.) G. Don or "kitolod" (Indonesia) is widely known as a traditional food medicine. However, the bioactive constituents of this plant are still unclear. Therefore, we investigated the bioactive compounds of H. longiflora (leaves and flowers) with Gas Chromatography-Mass Spectrometry (GC-MS) and further evaluated their potential biological activity. Ethanol extracts from the flowers and leaves of H. longiflora are targeted for phytochemical profiling of this plant. As a result, 16 metabolite compounds on leaves and 21 on flowers were successfully detected. A total of seven compounds, namely 2, 6, 10, 14, 18, 22-. Tetracosahexaene, 2, 6, 10, 15, 19, 23-hexamethyl-, (all--E)-, 2,6,10-Trimethyl, 14-Ethylene-14-Pentadecne, Stigmast-5-EN-3-OL, Stigmasterol, and Vitamin E dominate in both parts of this plant. The results of phytochemical analysis at the National Institute of Standard and Technique (NIST), H. longiflora can be an essential source of anti-tumor, anti-cancer, antibacterial, and antioxidant drugs.

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Keywords

Bioactive constituents, Hippobroma longiflora (L.) G. Don, GC-MS, Kitolod, Phytochemicals.

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