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Research Journal of Pharmacy and Technology
Year : 2023, Volume : 16, Issue : 12
First page : ( 5978) Last page : ( 5985)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2023.00970

Phytoconstituents profiling of Selaginella willdenowii (Desv.) Baker and Pharmacological Potential

Susilo Susilo*, Wardhani Ratih Kusuma

Department of Biology Education, Faculty of Teacher Training and Education, Universitas Muhammadiyah Prof. DR. Hamka, East Jakarta, Indonesia, 13830

*Corresponding Author E-mail: susilo@uhamka.ac.id

Online Published on 07 February, 2024.

Abstract

Selaginella willdenowii (Desv.) Bakeris a terrestrial herb with a high source of antioxidants. However, the phytoconstituents of these plants have not been reported. Therefore, we explored the metabolite in the leaves, stems, and roots of S. willdenowii (Desv.) Baker investigated its bioactive compounds' potential. Analysis of the phytoconstituents of S. willdenowii (Desv.) Baker ethanol extract was performed with Gas Chromatography-Mass Spectrometry (GCMS). We identified 69 metabolites that appear to be 16 categories of compound classes. 2,6,10-Trimethyl, 14-Ethylene-14-Pentadecne, Stigmasterol, Hexadecanoic, and acid methyl ester are four compounds consistently present in each part of the S. willdenowii (Desv.) Baker. Known pharmacological properties of phytocompounds found can be used as anticancer drugs, antioxidants, anti-inflammatory, antitumor, and antimicrobial. The identified phytoconstituents provide the foundation for utilizing S. willdenowii (Desv.) Bakeris a future ethnomedical, nutraceutical, and phytopharmaceutical source.

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Keywords

Antioxidants, Pharmacology, GC-MS, Natural product, Selaginella willdenowii (Desv.) Baker.

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