A Clinical Review on Ulcerative Colitis (Colon Cancer) Muthukumar A.1,*, Keserla Bhavani2,**, Abbas Syed Mohasin3,***, Thapa Reena4,****, Khatija Rumana5,***** 1Department of Pharmacology, Oxford College of Pharmacy, Bangalore, Karnataka, India 2Department of Pharmacology, Oxford College of Pharmacy, Bangalore, Karnataka, India 3Department of Pharmacology, Krupanidhi College of Pharmacy, Bangalore, Karnataka, India 4Department of Pharmacology, Krupanidhi College of Pharmacy, Bangalore, Karnataka, India 5Department of Pharmacology, Krupanidhi College of Pharmacy, Bangalore, Karnataka, India *Corresponding Author E-mail: drmkresearch14@gmail.com
**bhavanik76@gmail.com
***syedmohasinabbas14@gmail.com
****reenathakur@gmail.com
*****rumanakhatija@gmail.com
Online Published on 07 February, 2024. Abstract Ulcerative colitis (UC) is also known as colon cancer or colorectal cancer, a chronic inflammatory condition of the large intestine (colon and rectum). It comes under blood in stool, bowel urgency, fatigue, low energy, and rarely fever. Inulcerative colitis, the part of the colon's inner lining of unknown etiology involves the gastrointestinal tract. More than 80% of ulcerative colitis patients have the lining tissue of the inner rectum inflamed or has proctosigmoiditis, and less than 20% of patients haveextensive colitis. The case of UC has risenworldwide in the recent few decades, particularly in growing countries. The high-risk factors are family history, gender, race, and environmental factors contributing are smoking, infection taking Antibiotics, and NSAIDs. In 2013, Over 350,000 new cases of ulcerative colitis and over 125,000 Patients deaths were reported in the USA. Ulcerative colitis is different from Crohn's disease. However,in more the 50% of patients with mildsymptoms of proctosigmoiditis, some patients show proximal extension, and for some patients,opposition occurs with mild symptoms. Moreover, it is essential to identify the patients with some symptoms of ulcerative colitis to clinical risk factors that will help identify which patients are in the critical or higher stage of the disease proximal extension.The ulcerative colitis usually devolves between 20 to 30 years. Top Keywords Colorectal cancer, Corticosteroids, Immunomodulators, Crohn’s disease, Antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs). Top |