Baba Farid University Dental Journal
Year : 2011, Volume : 2, Issue : supl2
First page : ( 13) Last page : ( 15)
Print ISSN : 0976-8181. Online ISSN : 2230-7273.

Papillon Lefevre Syndrome- A Case Report

Nirola Ashutosh*, Professor and HOD, Gupta Madhu, Professor, Singla Kanika, Senior Lecturer

Address for Correspondence: Dr. Ashutosh Nirola, Professor and HOD, Department of Periodontology and Oral Implantology Luxmi Bai Institute of Dental Sciences and Hospital, Patiala, India

Online published on 7 December, 2011.

Abstract

Papillon Lefevre syndrome (PLS) is a rare autosomal recessive disease characterized by skin lesions which are manifested as palmar-plantar hyperkeratosis, severe periodontal destruction and precocious loss of teeth involving both the primary and permanent dentitions. PLS is caused by mutations in the cathepsin C gene located on chromosome 11 (11q14-q21). This report presents a 21 year old boy having the classic signs and symptoms of PLS.

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Keywords

Papillon Lefevre Syndrome, Palmar -plantar keratosis, Cathepsin C gene, Aggressive periodontitis.

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