Influence of dietary supplementation of lauric acid on blood parameters and antioxidant status in large white Yorkshire cross piglets Marsha G.G., Venkateswarlu M., Alexander G., Rao M. Hanumanth, Ekambaram B., Parashuramulu S.* College of Veterinary Science, P V. Narsimha Rao Telangana Veterinary University, Rajendranagar, Hyderabad-500 030, India *Correspondence, spramnutri@gmail.com
Online published on 28 December, 2023. Abstract To study the influence of lauric acid (LA) supplementation in the diets on blood biochemistry and oxidative stress in Large White Yorkshire cross (LWY) piglets, 28 piglets (70-75 days age) randomly allotted to 4 dietary treatments for 97 days. Basal diet (BD) was prepared without supplementation and an antibiotic (chlortetracycline at 0.05%) supplemented diet (BDA) was prepared as a positive control. The remaining two diets were prepared by supplementing LA at 0.2% (BDL-0.2) and 0.4% (BDL-0.4) to the BD. Blood biochemical parameters revealed that the total protein, albumin, globulin and total cholesterol levels were significantly (P<0.05) affected with LA supplementation, while glucose, blood urea nitrogen (BUN) and ratio of albumin: globulin were not affected by LA and antibiotic. The antibiotic and LA supplemented piglets had higher (P<0.05) total protein values, while lowest (P<0.05) values was recorded in BD group. Higher (P<0.05) serum albumin and globulin levels were recorded in piglets fed BDL-0.4 and was comparable to BDL-0.2 and BDA groups, with the lowest (P<0.05) values in BD group. Total cholesterol and lipid peroxidase (measure of oxidative stress) were highest (P<0.01) in BD fed group, while significantly (P<0.05) reduced in LA and antibiotic supplemented groups. Higher (P<0.01) activity of Glutathione peroxidase was observed with LA supplementation, while Catalase values did not differ between groups. It was concluded that LA supplementation in LWY piglets decreased the total cholesterol and increased the total protein, albumin and globulin contents in the blood with no effect on glucose and BUN contents. Further, reduced the oxidative stress by enhancing antioxidant enzyme activity and minimized the lipid peroxidation. Top Keywords Antibiotic, Antioxidant enzymes, Lauric acid, Piglets, Serum biochemistry. Top |