A study of comparison between ionized calcium and albumin corrected calcium in patients with chronic kidney disease Devi C. Suvarna1, Ramya R.2, Suma H. R.3, Naidu J. N.4, Naidu M. Prasad5,* 1Assistant Professor, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, 2Fellow in Cytogenetics, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, 3Associate Consultant, Dept. of Biochemistry, Sakra World Hospital, Bangalore, Karnataka, India 4Professor & HOD, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, 5Tutor, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, *Corresponding Author: Email: m.prasadnaidu@ymail.com
Online published on 2 January, 2019. Abstract Chronic kidney disease (CKD) is a global health issue rising in alarming rate. Diseases of mineral and bone metabolism are more common in chronic kidney disease. This study was aimed to evaluate comparison between ionized calcium and albumin corrected calcium in Subjects with CKD with dialysis treatment, to assess their calcium levels. Subjects with CKD on dialysis treatment, who presented to the Department of Medicine, PESIMSR, Kuppam were included into the study. Sample (n=40) was collected from all patients from AV fistula. This was used to analyze total calcium, serum albumin, pH and also ionized calcium values. Albumin corrected calcium is calculated using equation. The preliminary data analyses reporting a significant variation among ionized calcium and total calcium besides albumin corrected calcium in patients with CKD (p< 0.001). The factors that influence the ionized calcium levels are being currently determined. There is a significant variation among ionized calcium and total as well as albumin corrected calcium in subjects with CKD (P < 0.001). These results need further analyses to identify factors that influence ionized calcium levels. This will help us to know the importance of ionized calcium in estimating calcium levels in CKD subjects. Top Keywords Albumin, Total Calcium, Ionized Calcium, Dialysis, Chronic Kidney Disease. Top |