Study of micro-albuminuria in diabetic nephropathy Shivakumar1, Bharathi K. Prathibha2, Aruna P.3, Naidu J. N.4, Prasad M.4,* 1Assistant Professor, Sri Siddartha Medical College & Hospital, Agalakote, Tumkur, Karnataka 2Chief Consultant, Apollo & Hospital, Nellore, Andhra Pradesh 3Assistant Professor, Professor & HOD, ACSR Government Medical College and Hospital, Nellore, Andhra Pradesh 4PhD Scholar, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India *Corresponding Author: Email: drmprasad@narayanamedicalcollege.com
Online published on 2 January, 2019. Abstract The prevalence of diabetes mellitus is increasing worldwide. Recent studies showed that India has got large number of diabetic patients. Diabetic nephropathy (DN) develops in 30% to 40% of patients with type 1 diabetes mellitus and in 10% to 20% of patients with type 2 diabetes mellitus. Diabetic nephropathy is the leading cause of end-stage renal disease (ESRD) worldwide. An early sign of impending nephropathy is microalbuminuria. A total number of 90 samples were analyzed to study the microalbumin levels in 30 diabetic nephropathy patients, 30 diabetic patients without nephropathy and 30 healthy controls. The mean and standard deviation were calculated for all the parameters. The significance between the groups were determined using Student-test for Equality of means. The results show increase in mean concentration of microalbumin in diabetic nephropathy cases when compared to controls and was statistically highly significant (p< 0.001). The results were statistically significant (p< 0.001) in mean levels of Microalbumin in diabetic nephropathy cases when compared to diabetes mellitus without nephropathy cases. Top Keywords Micro albumin, Diabetic nephropathy, proteinuria, End Stage Renal Disease. Top |