A comparative study of efficacy and safety of 5% topical minoxidil with platelet rich plasma versus platelet rich plasma as a monotherapy in male patients with androgenetic alopecia Kamath Prashanth R.1,*, Goel Saumya2, Menon Ashok3, Babu Amita Murali4, Eram Hafsa4 1Assistant Professor, Dept. of Dermatology, Venereology and Leprosy, A.J. Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore, Karnataka, India 2Post Graduate, Dept. of Dermatology, Venereology and Leprosy, A.J. Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore, Karnataka, India 3Senior Resident, Dept. of Dermatology, Venereology and Leprosy, A.J. Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore, Karnataka, India 4Post Graduate, Dept. of Dermatology, Venereology and Leprosy, A.J. Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore, Karnataka, India *Corresponding Author: Email: prashanthkamath@gmail.com
Online published on 14 January, 2019. Abstract Introduction Male baldness is genetically determined, most common gradually progressive hair disorder leading to miniaturization of hair follicles. Various modalities have been used in various studies without significant results. Objective The aim was to study and compare the two modalities of treatment and to evaluate their results. Materials and Methods This is prospective, comparative study. Sample size was 40, twenty in each group. Group 1 was given 5% topical minoxidil solution two times in a day till six months and platelet rich plasma (PRP), Group 2 was given only PRP at three weekly interval for six months. Parameters evaluated before starting, after three months and after six months for-Hair pull test, anagen/telogen ratio, Patient's, Physician's assessment and clinical photographs. Results On evaluating group 1 showed relatively more significant improvement. On hair pull test significant reduction of hair breakage in group 1. Anagen/telogen ratio showed 8.9 ± 0.3% improvement in anagen hair in group 1 while 5.9 ± 0.5% was in group 2. Improvement was seen in patients of group 1 more than patients of group 2 based on patient's assessment and photographs. Conclusion 5% minoxidil when given with platelet rich plasma was superior and better when compared to platelet rich plasma alone. Top Keywords AGA, PRP, Minoxidil. Top |