Impact of psoriasis on serum lipid profile, CRP, ADA: A controlled study of 25 patients Vora Rita1,*, Surti Nishit2, Kota Rahul Krishna3, Patel Trusha4, Modasia Khushboo5 1Professor, Dept. of Skin & DVL, Pramukhswami Medical College, Gujarat, India 2Assistant Professor, Dept. of Skin & DVL, Pramukhswami Medical College, Gujarat, India 3Ex-Resident, Dept. of Skin & DVL, Pramukhswami Medical College, Gujarat, India 43rd Year Resident, Dept. of Skin & DVL, Pramukhswami Medical College, Gujarat, India 52nd Year Resident, Dept. of Skin & DVL, Pramukhswami Medical College, Gujarat, India *Corresponding Author: Email: ritavv@charutarhealth.org
Online published on 14 January, 2019. Abstract Introduction Psoriasis is a chronic disorder with certain systemic compounds. It has been associated with increase in morbidity and mortality from cardiovascular events especially in chronic cases. Aims and Objectives To compare the levels of CRP, S. ADA and S. Lipid profile among psoriatic patients and controls. Materials and Methods This is a cross sectional case control study conducted in department of dermatology for a period of 6 months in a teaching institute of Gujarat. Cases included patients of psoriasis attending skin OPD. Controls were taken from health check-up scheme of our hospital with minimal confounding factor. CRP, S. ADA and S. Lipid profile were assessed in both groups. Statistical Analysis We applied Unpaired T-test for statistical analysis and p value < 0.05 was considered significant. Results Patient and control group consisted of 25 subjects each. Serum CRP, serum cholesterol and serum TG levels were found to be more significantly elevated in cases when compared to controls with p-value (by unpaired t test) of 0.001, 0.026 and 0.044 respectively. Serum ADA, LDL, VLDL was high among cases when compared to controls but were not statistically significant. (p>0.05). Conclusion patients of psoriasis have to be evaluated for risk factors of atherosclerosis like Serum lipid profile, CRP. Top Keywords Psoriasis, CRP, ADA, Lipid profile. Top |