Calcium, phosphate and related hormonal profile in male and female senior citizens of Bangalore City Vybhavi Jyothi, Veeraiah Shivakumar1 Department of Physiology, Bowring and Lady Curzon Medical College and Research Institute, Bangalore, (Karnataka) 1Department of Physiology, Bangalore Medical College and Research Institute, Bangalore, (Karnataka) Online published on 23 December, 2020. Abstract This study was undertaken to estimate the extent of deficiency of Calcium, Phosphate, Vitamin D and parathyroid hormone in both male and female senior citizens of Bangalore city. 80 elderly persons (females 47 and males 33) of 60 years and above, who met inclusion and exclusion criteria, were selected after obtaining the ethical clearance. Written informed consent was taken from them. General physical examination and systemic examination were done, and anthropometric measurements were taken. Demographic characteristics, past medical history, medications and dietary intake were collected via questionnaires. 5 ml of venous blood sample was collected for serum analysis and estimation of serum Calcium, serum Phosphate, serum 25(OH)D and serum parathyroid hormone. Serum Calcium was estimated by Arsenazo III method, serum Phosphate by unreduced phosphomolybdate method and serum 25(OH)D and serum parathyroid hormone by Chemiluminescent Immunoassay, and all the results were statistically treated. The findings of this study revealed that there were normal serum levels of Calcium and normal serum levels of Phosphate, but decrease in serum levels of 25(OH)D and increase in serum parathyroid hormone levels were found in both the male and female study groups. When compared with male study group, females had significant decrease in serum 25(OH)D levels with P value of 0.048 and significant increase in serum parathyroid hormone levels with P value of 0.042. It may be concluded that the senescence accompanied by increased serum PTH and decreased serum 25(OH)D levels has maintained normal serum Calcium levels. Senescence and post menopausal combined effect has caused significant changes in females. Top Keywords Calcium, Phosphate, Vitamin D, Parathyroid Hormone, Ageing, Serum. Top |