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Canine melanoma: A case report Singh Surjeet1, Gupta R.P.1,*, Jangir B.L.1, Sharma Shrikant1, Soni Sapna1 1Department of Veterinary Pathology, College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar-125004, India *Corresponding author: e-mail: rpgupta2007@yahoo.co.in
Abstract A ten years old black female Labrador dog was presented to Private Pet Clinics, Delhi with history of anorexia and swelling near right eye since 6 months. On clinical examination, it revealed a small round growth. The growth was surgically excised. Grossly, it was black in colour, approximately 3 centimetres in diameter and soft in consistency. Histopathologically, it revealed pleomorphic epithelioid and fusiform shaped melanocytes with some of these neoplastic cells contained variable amount of melanin pigment in cytoplasm. On immunohistochemistry, it did not reveal any immunoreactivity for anti-pancytokeratin and anti-Ki67 antibodies. Based on the above findings, it was diagnosed as melanoma. Top Keywords Dog, Histopathology, Malignant melanoma. Top | ACKNOWLEDGEMENTS Authors are thankful to the Professor and Head, Division of Veterinary Pathology and Veterinary Surgery and Radiology, College of Veterinary Sciences, LalaLajpat Rai University of Veterinary and Animal Sciences, Hisar for providing necessaryfacilities to carry out this work. |
Top Figures Fig. 1.: A small round growth near right eye (arrow)in black coloured female Labrador dog
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| Fig. 2.: Excised black coloured round growth
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| Fig. 3.: Melanoma: pleomorphic epithelioid and fusiform shaped melanocytes. H&E ×200
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| Fig. 4.: Melanoma: neoplastic cells with large pleomorphic hyperchromatic nuclei containing prominent multiple nucleoli and indistinct cytoplasmic boundaries with variable amount of melanin pigment in cytoplasm and mitotic figures (arrows). H&E ×400.
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