Year : 2018, Volume : 42, Issue : 3
First page : ( 211) Last page : ( 212)
Print ISSN : 0250-4758. Online ISSN : 0973-970X. Published online : 2018 September 1.
Article DOI : 10.5958/0973-970X.2018.00051.2

Mixed germ cell and sex cord stromal tumour in a cryptorchid dog

Gopal K.^1,*, Pazhanivel N.¹, Jeyaraja K.¹, Kumar V.¹, Jayakumar K.¹, Ninu A.R.¹

¹Department of Veterinary Pathology, Veterinary College and Research Institute (TANUVAS, Chennai) Tirunelveli-627 358, India

*Corresponding author: e-mail: drvetpal@gmail.com

Received:  31  April,  2018; Accepted:  25  August,  2018.

Abstract

A seven year old male Spitz dog was presented for treatment with the history of dysuria for the past one week. Clinical examination revealed firm mass in the caudal abdomen and bilateral cryptorchid. Ultrasonography showed prostate hyperplasia and enlarged left testis resembling tumour. Histologically, the testicular tumour composed of neoplastic germ cells (seminoma cells) and sex cord stromal cells (sertoli cells). They were arranged in tubular structure. Based on the gross and histopathological features, the case was diagnosed as mixed germ cell and sex cord stromal tumour.

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Keywords

Dog, Mixed germ cell-sex cord stromal tumour, Pathology, Ultrasonography.

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Figures

Fig. 1.: Testis - Mixed germ cell - Sex cord stromal tumour- Trans abdominal ultrsonagraphy showing hypoechoic tumour mass TopBack

Fig. 2.: Testis - Mixed germ cell - Sex cord stromal tumour -Enlarged left testis and atrophied right testis TopBack

Fig. 3.: Testis - Mixed germ cell - Sex cord stromal tumour - Multilayered sertoli cells are arranged perpendicular to the basement membrane of the tubules whereas seminoma cells are at the centre. H&E ×200 TopBack

Fig. 4.: Testis - Mixed germ cell - Sex cord stromal tumour - The sertoli cells are elongate with small, oval to elongate nuclei and one or more nucleoli.The seminoma cells are large, round with large, vesicular and hyperchromatic nuclei and prominent nucleoli.H&E × 400 TopBack