An experimental study on gross and histopathological changes due to nano alumina (aluminium oxide/boehmite) feeding in white leghorn chickens Kuntal Naresh Singh*, Agarwal Seema, Chauhan R.S. Department of Veterinary Pathology, College of Veterinary and Animal Science, G.B.P.U.A.&T., Pantnagar, Uttarakhand-263145, India. Address for Correspondence Dr. Naresh Singh Kuntal, Ghari Vissa, Paintha, Mathura-281502, Uttar Pradesh, India, E-mail: nskuntal87@gmail.com
Abstract A study was conducted to understand the effects of nano alumina on White leghorn chickens of two week age. The chickens were randomly divided into two groups control and treated. The control group was fed with normal standard recommended feed while treated group exposed to nano alumina through oral route in feed for three months. The gross pathological study of experimental chickens in different groups was done after sacrifice of the chickens at the end of experiment (3 months post treatment). During necropsy there were no observable lesions found during external examination and after opening the carcass. Gross lesions like congestion, haemorrhage, emphysema, atalectesis and necrosis while, histopathological lesions like thickening, degeneration, necrosis, vacuolation, congestion, haemorrhage, emphysema, atalectesis, leucocytic infiltration and detachment of epithelium from basement membrane were observed in various organs like liver, kidney, lungs, intestine, testis, brain, spleen, thymus, bursa of Fabricius. Apart from these organs pathological changes were also seen in proventriculus, skeletal muscle and heart muscle. It was concluded that nanoalumina causes ill effects on the health status of chickens even at maximum tolerable level. Top Keywords Histopathological lesions, Nano alumina, Tolerable level, White leghorn chickens. Top |