Studies on pathomorphology of lungs of sheep and goat with special reference to Mannheimia haemolytica infection Swethashree M.J.1, Shilpa V.T.2, Girish B.C.2,*, Ravikumar P.2, Hegde Raveendra3, Ravikumar C.4, Manjunatha D.R.5 1Department of Veterinary Pathology, Veterinary College, Hassan, KVAFSU, Bidar 2Department of Veterinary Pathology, IAH & VB, Bengaluru 3SRDDL, IAH & VB, Bengaluru 4Department of Veterinary Pharmacology, IAH & VB, Bengaluru 5Veterinary Clinical Complex, IAH & VB, Bengaluru *Address for Correspondence B.C. Girish, Associate Professor and Head, Department of Veterinary Pathology, E-mail: girishhouse@gmail.com
Online Published on 2 January, 2024. Abstract Mannheimia infections are linked to improper management practices and can occur as a secondary infection or as a result of acute stress among domestic animals. The vulnerability of livestock to Mannheimia haemolytica pneumonia is increased by transportation stress, viral infections, crowded pens, inadequate housing conditions, rapid environmental fluctuation and other adversities. The aim of the present work was to record various gross and histopathological lesions of small ruminant lungs in Mannheimia haemolytica induced pneumonia and to confirm M. haemolytica using molecular technique. A total of 275 small ruminant carcasses were examined and lung lesions were recorded in 235 cases. On microscopic examination of 235 samples, 109 were found to be positive for bacilli. Pneumonic lesions were classified histopathologically into bronchopneumonia and interstitial pneumonia based on the degree of haemorrhage, congestion, amount of sero-proteinaceous fluid, type of inflammatory cells infiltrated like neutrophils, lymphocytes, macrophages, presence of fibrin, amount of fibrous connective tissues, type II pneumocyte proliferation, hyperplasia of bronchial and bronchiolar epithelium, peribronchial and peribronchiolar lymphoid aggregation and congestion. In the present study, bronchopneumonia was further classified into acute bronchopneumonia (44.17%), sub-acute bronchopneumonia (10%), suppurative bronchopneumonia (15.83%) and fibrinous bronchopneumonia (30%) while the inflammation was acute (100%) in all cases ofinterstitial pneumonia. PCR for Lkt gene of M. haemolytica was carried out on 109 lung tissue samples showed 22 (10.57%) positive cases, most of which were from cases of fibrinous bronchopneumonia (95.5%) and a few with suppurative bronchopneumonia (4.54%). It was found that M. haemolytica was stronglyassociated with fibrinous bronchopneumonia. Top Keywords Fibrinous bronchopneumonia, Goats, Lkt gene, Mannheimia haemolytica, sheep. Top |