Pathology of epitheliogenesis imperfecta in two herds of pigs Girish B.C.*, Shilpa V.T., Shivakumar M.C., Ravikumar P. Department of Veterinary Pathology, Veterinary College, Hassan, KVAFSU, Bidar *Address for Correspondence B.C. Girish, Associate Professor, Department of Veterinary Pathology, Veterinary College, Hassan, KVAFSU, Bidar, E-mail: girishhouse@gmail.com
Online Published on 2 January, 2024. Abstract Epitheliogenesis imperfecta (EI) is a clinically characteristic recessively inherited dermatological disorder affecting pigs. In the current investigation, two outbreaks have been recorded in herds of Large Yorkshire White piglets. Among the litter, 8/12 piglets (First outbreak) and 10/14 (Second outbreak) had classical clinical and gross pathological features of EI such as skin mal-formation on facial, leg and dorsal areas of the body that were devoid of epidermis and hairs. They appeared anorectic, weak, anemic and ataxic upon physical examination. The piglets with EI were vulnerable to conditions such as arthritis, diarrhea and pneumonia leading to mortality. Histopathological examination of the skin revealed loss of epidermis, epidermal hyperplasia, parakeratosis and hyperkeratosis. Few animals showed intensely eosinophilic radiating structures resembling Splendore-Hoep-pli bodies. Therapeutic intervention with antibiotics and topical antiseptics prevented occurrence of secondary pyoderma and consequent septicemia. Top Keywords Epitheliogenesis imperfect, Histopathology, Splendore-hoeppli bodies, Swine. Top |