Tissue tropism of porcine parvoviruses in naturally infected swine population of Punjab, India Kaur Parminder, Sethi R.S., Malik Yashpal Singh* College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141 004, Punjab, India *Address for Correspondence Yashpal Singh Malik, College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141 004, Punjab, India, E-mail: malikyps@gmail.com
Online Published on 2 January, 2024. Abstract Porcine parvovirus (PPV) is one of the major etiological agents responsible for reproductive health problems in porcine causing stillbirth, mummification, embryonic death, and infertility among swine. It attacks on host macrophages and makes the host more prone to infections. Therefore, the present study was undertaken to investigate the localization of PPV in different organs of the aborted fetus through immunohistochemistry. For this purpose, paraplast-embedded tissue samples of aborted fetus were treated using primary anti-PPV monoclonal antibody and HRP conjugated anti-mouse secondary antibody. The results obtained from present study revealed that an immunopositive reaction was found in the liver, lungs, and lymph node tissues of PPV-infected aborted fetus. The above data showed that PPV predilects in lung, liver and lymph nodes of the host. Top Keywords Immunohistochemistry, Macrophages, Porcine parvovirus, Tissue tropism. Top |