Fine needle aspiration cytology (FNAC) Vis-a-Vis histopathology for the diagnosis of canine hepatoid gland carcinoma - A case study Thakur Monika1,*, Gupta Kuldip2, Ramandeep3, Chauhan Neha1, Sharma Arvind1 1Zonal Veterinary Hospital, Barnoh, Distt Una, Himachal Pradesh 2Department of Veterinary Pathology, GADVASU, Ludhiana, Punjab 3Civil Veterinary Hospital, Nangal, Distt Rupnagar, Punjab *Address for Correspondence Monika Thakur, Veterinary Pathologist, Zonal Veterinary Hospital, Barnoh, Distt Una, Himachal Pradesh, India, E-mail: monikkathakur27@gmail.com
Online Published on 2 January, 2024. Abstract Hepatoid gland carcinomas (HGC) are relatively uncommon and accounts for 3-7% of all perianal neoplasms in canines. The present communication reports cytological, histopathological and radiographic findings in a rare case of hepatoid gland carcinoma involving tail region in eleven year old uncastrated male Labrador dog. On clinical examination, a solitary, raised, pea sized nodular mass was found over the proximal one third of the base of the tail. A routine complete blood count analysis was performed which showed borderline neutrophilic leucocytosis. Cytologic specimens prepared by Fine Needle Aspiration (FNA) revealed large hepatoid cells in sheets/clusters with vesicular nucleus and hyperchromatic nucleolus. Histopathological examination of excised mass revealed well-differentiated hepatoid cell population characterized by ample cytoplasm, eosinophilic granules and round nuclei with coarse chromatin. Thoracic radiographs revealed evidence of metastases in the lungs. Based on cytological and histopathological findings the mass was diagnosed as hepatoid gland carcinoma. The findings suggest that the FNAC technique could be of great use in the early presumptive diagnosis of canine hepatoid gland tumors. Top Keywords Canine, Fine-needle aspiration cytology, Hepatoid gland tumor, Histopathology, Malignancy, Radiographic examination. Top |