Malignant cutaneous mast cell tumour in a dog : A case report Kumar Sanjiv*, Tiwary Ramesh, Gopal Mutkule A., Patel Ritesh, Bhagat Puja K. Department of Veterinary Pathology, Bihar Veterinary College, Bihar Animal Sciences University, Patna-800 014, India *Address for Correspondence Sanjiv Kumar, Department of Veterinary Pathology, Bihar Veterinary College, Bihar Animal Sciences University, Patna-800 014, India, E-mail: mrsanvet@rediffmail.com
Online Published on 27 March, 2024. Abstract Mast cell tumours (MCTs) are one of the commonest malignant skin cancer in dogs. In the present case, an adult male Labrador dog, aged about 6 years was presented in the veterinary clinical complex having a history of gradually developing swelling in the left thigh on medial aspect of tibia and femur for diagnosis and treatment. The swelling was progressive and has grown to a very big size in a period of about 7 months, involving whole thigh region. The affected area was focally necrosed, ulcerated and-bleeding with a tendency of itching. On gross examination, the swelling appeared as large a covering a wide area with severe inflammation, purulent myositis and cellulitis. On careful examination, few very palpable small firm masseswereobserved surrounding the primary lesion. Blood samples, fine needle aspirates from the affected site and ultrasound guided aspirates from inguinal lymph nodes were collected for cytological examination. Tissue samples were also collected in 10% formalin for Histopathological procedure. Ultrasonography was also performed to ascertain the extent of spread. The haematological examination showed increased neutrophil and eosinophils with mild anaemia. Cytological evaluation of fine-needle aspirates revealed many pleomorphic, highly granulated mast cells while the histopathological examination showed masses consisting of sheets of neoplastic round nucleated mast cells with granules in the cytoplasm along with eosinophilic and neutrophilic infiltrations. The purpose of this paper is to provide diagnostic procedure of mast cell tumours while ultrasonography can be a practical method for determining its stage to some extent. Top Keywords Cytopathology, Dog, Mast cell tumour, Pruritus, Skin swelling, Ultrasonography. Top |