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Journal of PEARLDENT
Year : 2014, Volume : 5, Issue : 2
First page : ( 32) Last page : ( 37)
Print ISSN : 0976-0180. Online ISSN : 2229-4457.

Drug Eruptions Masquerading Stevens -Johnson syndrome - A Missed Diagnosis

Dr. Maloth Kotya Naik1,*, Dr. Reddy K. Vinay Kumar2, Dr. Velpula Nagalaxmi3, Dr. Meka Nagajyothi4, Dr. Sangmesh Mithare5

1Senior Lecturer, Dept of oral medicine and radiology, Mamata Dental College and Hospital, Khammam, Andhra Pradesh, India

2Professor & Head, Dept of oral medicine and radiology, Mamata Dental College and Hospital, Khammam, Andhra Pradesh, India

3Professor & Head, Dept of oral medicine and radiology, Sri Sai College Of Dental Surgery, Vikarabad, Andhra Pradesh, India

4Post Graduate Student, Dept of oral medicine and radiology, Sri Sai College Of Dental Surgery, Vikarabad, Andhra Pradesh, India

5Senior Lecturer, Dept of oral medicine and radiology, H K D E Trust's Dental College and Hospital, Humnabad, India

*Address For Correspondance: Dr. Kotya Naik. Maloth, Senior Lecturer, Department of Oral Medicine and Radiology, Mamata Dental College and Hospital, Giriprasad Nagar Khammam, Andhra Pradesh, India. Mobile: 91-9885617131. Email: dr.kotyanaik.maloth@gmail.com

Online published on 19 August, 2014.

Abstract

Stevens-Johnson syndrome (SJS) is a mucocutaneous disorder induced by an immune complex mediated hypersensitivity reaction with widespread erythematous, cutaneous macules, severe mucosal erosions or atypical targets nearly half of cases are caused by a reaction to drugs or appear during viral infections and malignancies. A very few cases are caused by a bacterial infection (Streptococcus) or Mycoplasma pneumoniae. We report a case of a 25 year old female patient diagnosed as Stevens-Johnson syndrome induced by the overdosage of outdated acetaminophen who was systemically treated with corticosteroids along with supportive therapy successfully over a period of 20 days in hospital care. Successful management entails the early identification and withdrawal of the offending drug or possible drug(s), transfer to a specialized centre and supportive care employing intensive multidisciplinary approach in a hospital.

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Keywords

Stevens-Johnson syndrome, adverse drug reaction, symptoms, management.

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