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Research Journal of Pharmacy and Technology
Year : 2023, Volume : 16, Issue : 1
First page : ( 8) Last page : ( 12)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2023.00002

Chito-oligosaccharides derived from Tilapia fish scales; A powerful antioxidant

Chaudhry Gul-e-Saba1,*, Thirukanthan CS1, Zin Nor Atikah Mohamed1, Yeong Yik Sung1, Muhammad Tengku Sifzizul Tengku1, Effendy AWM1,2

1Institute of Marine Biotechnology, University Malaysia Terengganu, 21030, Kuala Terengganu, Malaysia

2Faculty of Fisheries and Food Science, University Malaysia Terengganu, 21030, Kuala Terengganu, Malaysia

*Corresponding Author E-mail: gul.saba@umt.edu.my / sababiochem@gmail.com

Online Published on 10 October, 2023.

Abstract

Fish scales are a good source of chitin and collagen that can be used in various cosmetic, biomedical, pharmaceutical, and food industries due to their stability and environmental friendliness. The antioxidant activities of chito-oligosaccharides derived from fish scales evaluated via i) DPPH free radical scavenging activity, ii) superoxide anion radical scavenging activity, iii) ferrous ions chelating activity, and iv) reducing power analysis. The present work results indicated that chito-oligosaccharides (COS) derived from fish scales exhibited good antioxidant activities if compared against other sources of chitosan found in the literature. Thus, the development of bioactive products originated from fish scales could play a remarkable role in the sustainability and biomedical, food, and cosmaceuticals industries.

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Keywords

Antioxidant, Chito-oligosaccharides, DPPH, Tilapia fish, Reducing power, Chelating ability on ferrous ions, Superoxide scavenging assay.

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