Metabolomics: A step towards personalized periodontal diagnosis Meghana Ivaturi Sri Sai1, Bhat Amitha Ramesh2, Bhandary Rahul3 1Postgraduate Student, Periodontology, A B Shetty Memorial Institute of Dental Sciences, NITTE Deemed to be University, Deralakatte, Mangaluru, Karnataka 2Professor, Head of the Department Periodontology, A B Shetty Memorial Institute of Dental Sciences, NITTE Deemed to be University, Deralakatte, Mangaluru, Karnataka 3Professor, Periodontology, A B Shetty Memorial Institute of Dental Sciences, NITTE Deemed to be University, Deralakatte, Mangaluru, Karnataka Online Published on 5 February, 2024. Abstract A multifaced rather than streamlined approach has always been at the forefront of periodontal diagnostics. With the evolution of how diagnostic medicine is applied and executed, the ability to accurately anticipate the probability of dysbiosis in a patient has become the need of the hour. Translational metabolomics has already exhibited an astounding potential in the field of diagnostic medicine, both as an indicator as well as a predictor of disease activity. However, it is currently still an evolving technique and is not without its fair share of pitfalls. Addressing these lacunae and active research towards making it possible for implementation into clinical periodontal practice can be invaluable source and should be explored, more so now than ever with the constant evolution of disease pathogenesis and progression as well. The current paper focuses on the practical utility of the rapidly expanding plethora of metabolomics highlighting the concerns surrounding their applications in periodontal diagnosis. Top Keywords Metabolomics, Periodontal Medicine, Mass Spectroscopy, Saliva, Diagnosis. Top |