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BIOINFOLET - A Quarterly Journal of Life Sciences
Year : 2020, Volume : 17, Issue : 2
First page : ( 290) Last page : ( 294)
Print ISSN : 0973-1431. Online ISSN : 0976-4755.

Curcumin based therapeutics for liver health a review

Wasnik Ruchi, Bhatt Hirvita1

Department of Molecular Biology and Genetic Engineering, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra-440033, India

1Department of Pharmacognosy, Shree Dhanvantray Pharmacy Collegee, Kim, Surat, Gujarat-394111, India

Online published on 20 July, 2020.

Abstract

Nanotechnology has now become popular for offering effective chemicals useful for pharmaceutical purpose. Nano-formulation is an emerging area of research in the field of drug development. Several phytochemicals have been identified with excellent drug characteristics against liver ailments. However, there are limitations with respect to their isolation, purification, administration, absorption, metabolism and ultimately their efficacy as pharmaceutical product. Application of nanotechnology, may to some extent can help in resolving these limitations. In this context, several nano-phytoformulations have emerged and their investigations have been conducted. Present review gives information on nano-formulations made from curcumin and its medicinal value relating to liver health. The nano formulations checked for encapsulation efficiency, effective dose, target specificity and overall efficacy. Except nanoparticles of curcumin, none of other nano-phyto-formulation with hepato-protective efficacy are available in the market, and most of the studies remained confined to the research laboratories.

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Keywords

Hepatotoxicity, nano-formulations, bioavailability, curcumin.

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