A Study of Role of Antibiotics in Cases of Acute Pancreatitis in Western Uttar Pradesh Sharma Dhawal, Post Graduate Student Third Year, Gupta Atul Kumar, Associate Professor, Gupta Shalabh, Professor, Head of Department, Bhagat T S, Professor, Unit Head, Verma Rajiv, Assistant Professor, Vardhan Prateek, Post Graduate Student Third Year, Rai Mamta, Post Graduate Student Third Year Deptt. of General Surgery, Santosh Medical College & Hospital Online published on 7 October, 2013. Abstract Acute pancreatitis is a protean disease capable of wide clinical variation, ranging from mild discomfort to apocalyptic prostration. Infectious complications with incidence of 40–70% in severe acute pancreatitis are predominant cause of morbidity and mortality. The role of prophylactic antibiotic therapy in Acute Pancreatitis is still not clear. To assess the frequency of infection & role of antibiotic therapy in Acute Pancreatitis a study was conducted on 24 patients in Department of Surgery, Santosh Medical College & Hospital, Ghaziabad. All the patients underwent all specific investigations and managed with only supportive treatment unless infection was proven. In our study it was observed that frequency of infection in acute pancreatitis is 4.16% and appropriate supportive therapy is the mainstay of management of acute pancreatitis. Antibiotics are required in acute pancreatitis only when there is a definite evidence of infection in terms of positive culture sensitivity or any intervention is done. Appropriate surgical intervention is the treatment of choice in those with infected pancreatitis. Top Keywords Acute Pancreatitis, Antibiotics, Infection. Top |