Cicatricial pemphigoid – A case report and review of literature Dr. Kaur Beant1,,*, Dr. Singh Param Pal2, Dr. Trivedi Ashwarya2, Dr. Dua Nisha3, Dr. Singla Neetu3, Dr. Khosa Rameen4 1PG Student, Dept. of Oral Medicine and Radiology, GNDDC, Sunam 2Reader, Dept. of Oral Medicine and Radiology, GNDDC, Sunam 3Senior Lecturer, Dept. of Oral Medicine and Radiology, GNDDC, Sunam 4Senior Lecturer, Dept. of Oral Medicine and Radiology, Surindra Dental College, Shri Ganganagar *Corresponding Author: Dr. Beant Kaur Sidhu, PG Student, Dept. Oral medicine and radiology, Gurunanak dev dental college & ri, sunam
Online published on 25 December, 2013. Abstract More than 50 years have passed since Civatte, Lever, and others described the clinical and histopathological characteristics of mucous membrane pemphigoid (synonym: cicatricial pemphigoid). This enigmatic, relapsing, and often eventually progressive subepithelial blistering disorder of the mucous membranes and skin continues to challenge investigators trying to understand the pathogenesis of the disease and prevent its progression. Mucous membrane pemphigoid typically begins in late adulthood and has a variable prognosis. Fifty percent of patients will develop esophageal and ocular lesions that heal with secondary atrophy leading to stenosis of the upper aerodigestive tract and blindness in uncontrolled disease. Recent progress has been made in understanding the cause, the immunological components, and the pathologic process of mucous membrane pemphigoid. The short-term clinical and pathological manifestations of disease activity have been reduced by new therapies, although the degree of long-term benefit from these treatments awaits further study. Here we are presenting a case report of Cicatricial pemphigoid in a 70 years old female with involvment of conjunctiva & oral mucosa in addition to skin lesion. Diagnose was confirmed by histopathologically as Cicatricial Pemphigoid. Top Keywords Autoimmune, Cicatricial pemphigoid, Corticosteroid. Top |